Ewan McGregor (Tom Lincoln / Lincoln Six Echo), Scarlett Johansson (Sarah Jordan / Jordan Two Delta), Djimon Hounsou (Albert Laurent), Sean Bean (Dr. Bernard Merrick), Steve Buscemi (James McCord), Michael Clarke Duncan (Jamal Starkweather / Starkweather Two Delta), Ethan Phillips (Jones Three Echo), Brian Stepanek (Gandu Three Echo), Shawnee Smith (Suzie), Svetlana Efremova (Hebamme), Kim Coates (Charles Whitman), Tim Halligan (Gerichtsmediziner), Max Baker (Leiter Inkubation), Phil Abrams (Obgyn)